Chris Sale was a 2001 participant at Cooperstown Dreams Park with the Auburndale Storm (FL) during week 6. In 2010, he was chosen by the Chicago White Sox as the 13th first-round pick of Major League Baseball's amateur draft.

Chris graduated from Lakeland High School (Lakeland, FL) in 2007. He was also selected as a 21st round draft selection by the Colorado Rockies. Instead of making the jump to the professionals, Chris enrolled and attended Florida Golf Coast University (Fort Myers, FL).

A left-handed pitcher, Chris recorded 21 appearances on the mound, all but one in relief He finished the year with a 2-0 record with two saves, throwing 36.1 innings with 46 strikeouts and only nine walks. Chris had a 3.47 ERA and held opponents to a .250 batting average. He was chosen to the Freshman All A-Sun team.

As a sophomore, Chris appeared in 14 games, making 12 starts. He went 7-4 with 104 strikeouts, throwing 89.1 innings with a 2.72 ERA. Chris ERA was first on the team as well as his opposing batting average (.246), innings pitched (89.1), and strike outs (104). He was second in the A-Sun in ERA and strike outs, tied for second in the A-Sun in wins, and third in innings pitched. Chris was named A-Sun player of the week on Mar. 30 and earned All-Atlantic First Team honors.

During his junior year, Chris earned BFC Outstanding Pitcher Award for the 2009 Cape Cod Baseball League Season after leading the league in strikeouts and innings pitched. He was named top prospect in Cape Cod League by Baseball America and earned Louisville Slugger Preseason Second Team All-American honors selected by Collegiate Baseball newspaper.

After his junior collegiate season, Chris made the decision to turn professional, signing with the Chicago White Sox. He was first assigned with single A Winston-Salem Dash (Winston-Salem, NC), pitching in 4 games (0-0 record, 2.25 ERA in 4 innings). Chris was promoted to the AAA Charlotte Knights (Fort Mill, SC), throwing in 7 games (0-0 record, 2.84 ERA). On August 4, 2010, Chris was called up to the majors, making his debut on August 6, 2010 against the Baltimore Orioles. The first 2010 major league draft pick to be promoted to the majors, Chris continues to pitch for the Chicago White Sox as a closer.