Delino DeShields was a member of the 2005 N.A.T.C. champions at Cooperstown Dreams Park, the Boys of Baseball National Travel Team (an organization based out of Alabama). During the 2010 Major League Baseball Amateur draft, Delino became a first-round pick, being chosen eighth by the Houston Astros.

Just prior to his first-round pick, Delino graduated from Woodward Academy (College Park, GA). Delino played centerfield for Woodward Academy, helping the War Eagles capture the 2010 Region 4-AAA Championship. He recorded 29 stolen bases and .415 BA with nine home runs during his senior year. Delino was one of eight players from his team to be named to the Region 4-AAA All Region Team 1st Team roster.

Delino did sign a letter of intent to play baseball at Louisiana State University (Baton Rouge, LA). However, he decided not to pursue a college career and signed with the Houston Astros. Delino began his professional career in 2010 with the Rookie League's Gulf Coast Astros (Florida). After two games, he went to another Rookie League team, Greenville Astros (Greenville, TN). In 2011, he was promoted to the Class A Lexington Legends (Lexington, KY) where he continues to be listed on the roster as the team's second baseman.