In 1998, Trevor Plouffe competed at Cooperstown Dreams Park during N.A.T.C. with the SoCal Angels (CA). Twelve years later (May, 2010) he made his major league debut with the Minnesota Twins.

Trevor is a 2004 graduate of Crespi Carmelite High School (Encino, CA). During his senior year, Trevor batted .509 (28-55) with six home runs, 20 runs batted in, 23 runs, and 10 stolen bases. He was named a 2004 "Collegiate Baseball News" High School All-American. After graduation, Trevor was drafted by the Minnesota Twins as the 20th overall pick. He spent the 2004 season with the Rookie-level Elizabethton Twins (Eizabethon, TN).

Trevor spent several years in the minors, splitting the 2008 season between the Double-A New Britain Rock Cats (New Britain, CT) and Triple-A Rochester Red Wings (Rochester, NY). He was added to the Minnesota Twins Major League 40-man roster after the 2008 season. On May 20, 2010, Trevor was called up to the Minnesota Twins. Before retiring at the 2018 season, Trevor played with the Oakland Athletics, Tampa Bay Rays, Texas Rangers, and Philadelphia Phillies.